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Gender-based considerations The phase 2 trial included both men and women, and the results did not show statistically significant differences in weight loss between genders at matched doses
Costs included drug acquisition and administration, using current NHI prices
Through promoting lipolysis in adipose tissue, IR is believed to exacerbate lipotoxicity, which is positive feedback further aggravating the imbalance of metabolism (121)
any adjustments should always align with current health status and weight management goals
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